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Title:Home | Multiple Myeloma Research Foundation
Description:The Multiple Myeloma Research Foundation — the MMRF — is working to find a cure for every patient diagnosed with multiple myeloma.
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-- Coronavirus & Multiple Myeloma: Latest Updates Multiple Myeloma Multiple Myeloma Diagnosis Prognosis Understanding survival statistics Treatment options Standard treatments Stem cell transplants Clinical trials and experimental therapies Supportive care Treatment guides Symptoms & side effects Glossary Finding a Cure Finding a Cure Our achievements Our approach Our work Immunotherapy Myeloma Investment Fund CureCloud ® CoMMpass ℠ Study Multiple Myeloma Research Consortium MyDRUG clinical trial Resources Resources Patient Navigation Center The Right Track Education programs Find a support group Financial assistance Myeloma Mentors Find a treatment center Clinical trial finder About About News, press and blogs Executive leadership Board of directors Honorary board Financials Get Involved Get Involved Participate in research Ways to donate Join an event Patient Navigator Patient Navigator Donate Our mission: cure multiple myeloma The Multiple Myeloma Research Foundation (MMRF) drives discoveries for new treatments, accelerates groundbreaking clinical trials and fuels the most robust data-driven initiatives in cancer research. Our goal is to find a cure for each and every patient diagnosed with multiple myeloma. The latest from The MMRF MMRF Blogs MMRF Venture Philanthropy Fund Invests in Cullinan MICA to Bring First-In-Class Immuno-Oncology Antibody into the Clinic MMRF Blogs Equality, Inclusivity & Commitment to Our Community MMRF Blogs MMRF Virtual ASCO 2020 Meeting Blogs MMRF in the News Managing Through Crisis: Why Urgency Can Bring Clarity Scientific/Research Publications Building to the Pinnacle of Precision Medicine MMRF Blogs MMRF in the News MMRF Founder Kathy Giusti with a Message for Patients MMRF in the News Kathy Giusti: War on coronavirus can teach us how to more effectively wage war on cancer MMRF in the News MMRF Founder Kathy Giusti on Everyone Talks to Liz Claman MMRF Blogs Multiple Myeloma & COVID-19 Guidelines for Health Care Providers Understanding multiple myeloma Discover more information about multiple myeloma, such as symptoms, side effects, treatment options and more. More about multiple myeloma What do I do now? One Get informed Talk to our trained professionals Talk to a myeloma expert at our Patient Navigation Center who can help you understand your diagnosis, provide support and answer questions. Let's talk Get important information you need Sign up to learn about clinical trials, treatment options and the latest news to help you make the right decisions. Sign up Two Find the right track for treatment The MMRF’s Right Track program puts you on the path to the best results for you. THE RIGHT TRACK ™ Right Team Access experts and centers that have extensive experience treating multiple myeloma Right Tests Get the information, tests and precise diagnoses to make the right treatment decisions Right Treatment Work with your team to decide on the best treatment plan and identify clinical trials that are right for you Get on the right track Three Join our study to find personalized treatments Participate in the MMRF CureCloud The MMRF CureCloud® is a research study that includes the first at-home genomic testing program. This comprehensive data hub of clinical and genomic information can help researchers, clinicians and patients make smarter treatment decisions. Join The MMRF CureCloud Unprecedented results The MMRF’s patient-centered approach is changing cancer research. We’re problem solvers and innovators. Over the years, we’ve found original and creative ways to speed research, fund initiatives and break through the institutional barriers that can slow progress. Our unrelenting focus is on helping every patient find the right treatment. Finding a cure $ 500 M invested in research 12 drugs brought to market 3 x increase in life expectancy As a patient and someone who had worked in the pharmaceutical industry, I could see the challenges in the healthcare system, and I could also see ways to solve them. Kathy Giusti, Founder The MMRF Get involved Upcoming 01 September Team for Cures MMRF Virtual 5K Walk/Run Programs Team for Cures Be part of our Team for Cures program, which brings together the myeloma community and supporters to raise funds for research and celebrate progress. Take part in our 5K Walk/Run program, one of our Endurance Events or host your own event via the Independent Events program or through our Young Professional program. View events Signature events Join the MMRF community of patients, caregivers, medical and research leaders, business executives, philanthropists and celebrities at our high-impact signature events that educate and empower while raising necessary funds and awareness for multiple myeloma. View events 383 Main Avenue, 5th Floor Norwalk, CT 06851 1-203-229-0464 Contact Us Careers Our sponsors Research grants Privacy policy Donor privacy policy Terms of use The MMRF is a registered 501(c)(3) non-profit. Tax ID: 06-1504413 For donations please mail to: P.O. Box 414238 Boston, MA 02241-4238 © 2020, Multiple Myeloma Research Foundation, Inc. Donate Patient Navigator Donate Contact Name Email Phone Subject Description Captcha: Please enter number displayed in textbox. Submit Revised International Staging System (R-ISS) Criteria Stage Criteria I ß2-M less than or equal to 3.5mg/L and albumin greater than or equal to 3.5 g/dL Absence of higher-risk DNA abnormalities Normal lactate dehydrogenase (LDH) II Not Stage I or III III ß2-M greater than or equal to 5.5mg/L and either Presence of higher-risk DNA abnormalities or High LDH ß2-M = beta2-microglobulin Higher-risk DNA abnormalities include del(17p) and/or translocation (t4;14) and/or translocation (14;16) LDH = lactate dehydrogenase Measuring your prognosis Test Indication Values Indicating a More Favorable Prognosis Beta 2-microglobulin (β2-microglobulin or β2-M) Higher levels reflect more extensive disease and poor kidney function. <3.5 mg/mL Albumin level Higher levels may indicate better prognosis. ≥3.5 g/dL Lactate dehydrogenase (LDH) level Higher levels indicate more extensive disease. Age ≤60yrs.: 100-190 U/L Age >60yrs.: 110-210 U/L Freelite® serum free light chain assay Abnormal results may indicate poor prognosis (also indicates risk of progression of MGUS or asymptomatic myeloma to symptomatic myeloma). Free light chain ratio MGUS: 0.26-1.65 Asymptomatic myeloma: 0.125-8.0 Symptomatic myeloma: 0.03-32 Chromosome analysis (cytogenetic testing by either karyotyping or FISH) Presence of specific abnormalities may indicate poor prognosis. Absence of abnormalities Gene expression profiling Presence of specific group of genes can predict low or high risk of early relapse. Personalize risk score Patient Webinar Webinar Topic Date Learn Your Labs Tuesday, February 4, 2020 1:00PM ET View Recording View Slides Supportive Care Wednesday, March 4, 2020 1:00PM ET View Recording View Slides Smoldering Myeloma Thursday, April 23, 2020 1:00PM EDT View Recording Accredited activities Topic Date Link Current Obstacles in Myeloma Management: Debating the Evidence Expires: January 25, 2021 Register Shaping the Future of Myeloma Treatment Expires: July 11, 2020 Register Patient toolkit Program Chair(s) Date Location of Event Access Link Program Chair Robert Z. Orlowski MD, PhD Elisabeth E. Manansanch, MD May 21, 2020 Virtual View Recording View Slides Patient toolkit Title Download Links Managing Myeloma Resource Brochure English Spanish Multiple Myeloma Disease Overview English Spanish Multiple Myeloma Treatment Overview English Spanish Multiple Myeloma Caregiver Guide English Spanish Precision Medicine Brochure English Spanish Immunotherapy English Spanish Register to speak to a myeloma mentor Contact Name Email Phone Requested Mentor's Name: Subject Description Captcha: Please enter number displayed in textbox. Let’s connect Contact the MMRF with any questions or comments—whether you are a patient, caregiver, researcher or clinici...
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